科学研究
潘燕
 

潘燕,1979年出生,博士。2011年毕业于复旦大学放射医学专业,现任复旦大学放射医学研究所副研究员。近年来,主持国家自然科学基金面上项目、青年项目,科技部国家重大仪器专项子课题,上海市卫生局人才基金,并获复旦大学卓学人才计划支持;作为主要成员先后参与了国家自然科学面上项目、教育部新世纪人才基金、上海市重点学科项目、以及国家自然科学基金重点项目等多个研究项目,已发表SCI收录论文多篇,获专利1项。

联系方式:swallowpan@fudan.edu.cn

                    021-64436720

联系地址:上海市徐汇区斜土路20941号楼227


通讯作者论文

1Hang Zhang, Cuiping Zhou, Yang Bai, Dexiao Yuan, Yan Pan*, Chunlin Shao*. Blocking endogenous H2S signaling attenuated radiation-induced long-term metastasis of residual HepG2 cells through inhibition of EMT. Radiation Research.2018 190: 374-384.


第一作者论文

1Y Pan, CP Zhou, DX Yuan, JH Zhang, CL Shao*. Radiation Promotes Hepatocarcinoma Cell Invasiveness through Epithelial Mesenchymal Transition Mediated by H2S/CSE Pathway. Radiation Research. 2016 Jan;185(1):96-105.

2Y Pan, S Ye, DX Yuan, JH Zhang, CL Shao*.  H2S/CSE pathway contributes to the malignant proliferation of hepatoma cells. MUTAT RES-FUND MOL M  2014, 763-764 (2014) 10-18. 

3Y Pan, S Ye, DX Yuan, JH Zhang, Y Bai, CL Shao*.Radioprotective role of H2S/CSE pathway in Chang liver cells. MUTAT RES-FUND MOL M  2012, 738-739: 12-18. 

4Y Pan, DX Yuan, JH Zhang, CL Shao*. Cadmium induced radioadaptive response via an ATM-independent H2S/cystathionine -γ-lyase modulation. MUTAT RES-FUND MOL M  2011, 707:67-73.

5Y Pan, DX Yuan, CL Shao*. Cadmium-induced adaptive response in Chinese hamster ovary cells with varying DNA repair capacity. Radiation Research, 2009, 171:446-453. 

6潘燕, 华国强, 邵春林*.肠道干细胞在高剂量辐射后大小肠放射敏感性差异中的作用, 中华放射医学与防护杂志, 权威2015, 35(6):7-12

7潘燕, 袁德晓, 邵春林*. 细胞适应性反应分子机制研究进展. 中华放射医学与防护杂志, 权威2009,29(4):466-470

8潘燕,袁德晓, 邵春林*. DNA损伤修复在镉诱导的细胞辐射适应性中的作用.中华放射医学与防护杂志, 权威 2008,28(5):466-470.


其他论文

1Hua G Wang C, Pan Y, Zeng Z, Lee SG, Martin ML, Haimovitz-Friedman A, Fuks Z, Paty PB, Kolesnick RN*. Distinct levels of radioresistance in Lgr5+ colonic epithelial stem cells versus Lgr5+ small intestinal stem cells. CANCER RESEARCH. 2017 Feb 15. pii: canres.2870.2015. doi: 10.1158/0008-5472. CAN-15-2870.

2Yuan D, Xu JPWang, JPan YFu JMBai YZhang, JH*Shao, CL*, Extracellular miR-1246 promotes lung cancer cell proliferation and enhances radioresistance by directly targeting DR5, Oncotarget2016.5.31, 7 (22): 32707-32722.

3Ye S, Yuan D, Xie Y, Pan Y, Shao C*. Role of DNA methylation in the adaptive responses induced in a human B lymphoblast cell line by long-term low-dose exposures to γ-rays and cadmium.  MUTAT RES-GEN TOX EN. 2014 Oct; 773: 34-8.

4Liu W, Xiao L, Dong C, He M, Pan Y, Xie Y, Tu W, Fu J, Shao C*. Long-term low-dose α-particle enhanced the potential of malignant transformation in human bronchial epithelial cells through MAPK/Akt pathway. BIOCHEM BIOPH RES CO. 2014 May 9; 447 (3): 388-93.

5MY He, C Dong, R Ren, DX Yuan, YX Xie, Y Pan, CL Shao*. Radiation Enhances the Invasiveness of Irradiated and Nonirradiated Bystander Hepatoma Cells Through a VEGF-MMP2 Pathway Initiated by p53. Radiat Res. 2013 Oct; 180 (4): 389-97.

6DX Yuan, Ye S, Y Pan, YZ Bao, HH Chen, CL Shao*. Long-term cadmium exposure leads to the enhancement of lymphocyte proliferation via down-regulating p16 by DNA hypermethylation. MUTAT RES-GEN TOX EN 2013 Oct; 757(2):125-31.

7S Ye, DX Yuan, YX Xie, Y Pan, CL Shao*. Role of DNA methylation in long-term low-dose γ-rays induced adaptive response in human B lymphoblast cells. Int J Radiat Biol. 2013 Nov; 89(11): 898-906.

8JH Zhang, YX Xie, YW Xu, Y Pan, CL Shao*. Hydrogen sulfide contributes to hypoxia-induced radioresistance on hepatoma cells. J Radiat Res. 2011; 52(5): 622-8.

9DX Yuan, Y Pan, J. Zhang, C. Shao*. Role of nuclear factor-B and P53 in radioadaptive response in Chang live cells, MUTAT RES-FUND MOL M . 2010, 688(1-2):66-71.

10)袁德晓, 潘燕, 邵春林*. DNA损伤修复能力对辐射适应性效应的影响. 核技术. 2009, 32 (5): 366-370.

11)叶爽, 袁德晓, 谢月霞, 潘燕, 邵春林*. 长期低剂量γ照射对人B巴母细胞辐射敏感性的影响. 中华放射医学与防护杂志, 权威2013 33 (3): 256-262

12)袁德晓, 潘燕, 邵春林*. DNA损伤修复能力对辐射适应性效应的影响. 核技术. 核心2009, 32 (5): 366-370.


会议论文

1潘燕, 张江虹, 谢月霞, 叶爽, 袁德晓, 邵春林*. H2S对肝细胞辐射保护作用的分子机制研究, 中国毒理学会放射毒理专业委员会第九次全国学术会议, 中国重庆201210  

2潘燕, 袁德晓, 邵春林*. 硫化氢对辐射损伤细胞的保护作用, 首届华人辐射研究大会中国西安20114

3潘燕, 袁德晓, 邵春林*. DNA损伤修复在镉诱导的细胞辐射适应性中的作用, 第五次全国放射医学与防护青年学术交流会议优秀论文中国西


授权发明专利:

邵春林(#), 袁德晓, 叶爽, 潘燕, 张江虹, 白杨. 一种检测电离辐射剂量的生物学方法, 2012.6.20, 中国, CN201110333811.X

获得学术奖励:

潘燕(4/6), 一种检测电离辐射剂量的生物学新方法, 上海市知识产权局, 27届上海市优秀发明选拔赛优秀发明奖, 金奖, 2015(邵春林, 袁德晓, 叶爽, 潘燕, 张江虹, 白杨)